Bis(phenylethynyl)arene Linkers in Tetracationic bis-Triarylborane Chromophores Management Fluorimetric and Raman Sensing of Numerous DNA and RNA
We report Four new luminescent tetracationic bis-triarylborane DNA and RNA sensors that present excessive binding affinities, in a number of instances even within the nM vary. Three of the compounds comprise substituted, extremely emissive, and structurally versatile bis(2,6-dimethylphenyl-4-ethynyl)arene linkers (3: arene=5,5′-2,2′-bithiophene; 4: arene=1,4-benzene; 5: arene=9,10-anthracene) between the 2 boryl moieties and function environment friendly twin Raman and fluorescence chromophores.
The shorter analogue 6 employs bis(2,6-dimethylphenyl)-9,10-anthracene because the linker and demonstrates the significance of an satisfactory linker size with a sure degree of flexibility by exhibiting typically decrease binding affinities than 3-5. Pronounced aggregation-deaggregation processes are noticed in fluorimetric titration experiments with DNA for compounds Three and 5. Molecular modelling of complexes of 5 with AT-DNA, counsel the minor groove because the dominant binding web site for monomeric 5, however exhibit that dimers of 5 can be accommodated. Sturdy SERS responses for 3-5 vs. a really weak response for six, notably the robust indicators from anthracene itself noticed for five however not for six, exhibit the significance of triple bonds for robust Raman exercise in molecules of this compound class.
The vitality of the attribute stretching vibration of the C≡C bonds is considerably depending on the fragrant moiety between the triple bonds. The insertion of fragrant moieties between two C≡C bonds thus presents another design for twin Raman and fluorescence chromophores, relevant in multiplex organic Raman imaging

bio-tech-inc
DNA / RNA Damage Antibody |
abx444253-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx444534-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx444884-100l |
Abbexa |
100 µl |
EUR 337.5 |
DNA / RNA Damage Antibody |
20-abx444884 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
DNA / RNA Damage Antibody |
abx440040-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx440321-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx440602-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx440883-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx441164-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx441445-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx441726-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx442007-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx442288-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx443130-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx443410-100ug |
Abbexa |
100 ug |
EUR 644.4 |
|
DNA / RNA Damage Antibody |
abx443691-100ug |
Abbexa |
100 ug |
EUR 678 |
|
DNA / RNA Damage Antibody |
abx442569-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA / RNA Damage Antibody |
abx442850-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
DNA/RNA Damage Antibody |
MBS8001907-0025mg |
MyBiosource |
0.025mg |
EUR 265 |
DNA/RNA Damage Antibody |
MBS8001907-5x0025mg |
MyBiosource |
5x0.025mg |
EUR 925 |
DNA/RNA Damage Antibody |
MBS801590-01mg |
MyBiosource |
0.1mg |
EUR 415 |
DNA/RNA Damage Antibody |
MBS801590-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1595 |
DNA/RNA Damage Antibody |
SMC-155D |
Stressmarq |
0.1mg |
EUR 214.2 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA/RNA Damage Antibody |
SMC-155S |
Stressmarq |
0.012mg |
Ask for price |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA / RNA Damage Antibody (PE) |
abx444253-100g |
Abbexa |
100 µg |
EUR 575 |
DNA / RNA Damage Antibody (HRP) |
abx443410-100g |
Abbexa |
100 µg |
EUR 562.5 |
DNA / RNA Damage Antibody (APC) |
abx442569-100l |
Abbexa |
100 µl |
EUR 575 |
DNA/RNA Damage Antibody: HRP |
MBS801864-01mg |
MyBiosource |
0.1mg |
EUR 450 |
DNA/RNA Damage Antibody: HRP |
MBS801864-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1770 |
DNA/RNA Damage Antibody: RPE |
MBS803622-01mg |
MyBiosource |
0.1mg |
EUR 460 |
DNA/RNA Damage Antibody: RPE |
MBS803622-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1820 |
DNA/RNA Damage Antibody: APC |
SMC-155D-APC |
Stressmarq |
0.1mg |
EUR 250.6 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA/RNA Damage Antibody: HRP |
SMC-155D-HRP |
Stressmarq |
0.1mg |
EUR 241.5 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA/RNA Damage Antibody: RPE |
SMC-155D-RPE |
Stressmarq |
0.1mg |
EUR 248.5 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA / RNA Damage Antibody (FITC) |
abx443130-100g |
Abbexa |
100 µg |
EUR 575 |
DNA/RNA Damage Antibody: FITC |
MBS803261-01mg |
MyBiosource |
0.1mg |
EUR 455 |
DNA/RNA Damage Antibody: FITC |
MBS803261-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1790 |
DNA/RNA Damage Antibody: FITC |
SMC-155D-FITC |
Stressmarq |
0.1mg |
EUR 245 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA / RNA Damage Antibody (PerCP) |
abx443972-100g |
Abbexa |
100 µg |
EUR 575 |
DNA/RNA Damage Antibody: PerCP |
MBS802697-01mg |
MyBiosource |
0.1mg |
EUR 465 |
DNA/RNA Damage Antibody: PerCP |
MBS802697-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1830 |
DNA/RNA Damage Antibody: PerCP |
SMC-155D-PCP |
Stressmarq |
0.1mg |
EUR 250.6 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA / RNA Damage Antibody (Biotin) |
abx442850-100g |
Abbexa |
100 µg |
EUR 575 |
DNA/RNA Damage Antibody: Biotin |
MBS803145-01mg |
MyBiosource |
0.1mg |
EUR 460 |
DNA/RNA Damage Antibody: Biotin |
MBS803145-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1815 |
DNA/RNA Damage Antibody: Biotin |
SMC-155D-BI |
Stressmarq |
0.1mg |
EUR 247.8 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA / RNA Damage Antibody (ATTO390) |
abx440040-200g |
Abbexa |
200 µg |
EUR 587.5 |
DNA / RNA Damage Antibody (ATTO488) |
abx440321-100g |
Abbexa |
100 µg |
EUR 587.5 |
DNA / RNA Damage Antibody (ATTO594) |
abx440883-100g |
Abbexa |
100 µg |
EUR 587.5 |
DNA/RNA Damage Antibody: ATTO 594 |
MBS800732-01mg |
MyBiosource |
0.1mg |
EUR 465 |
DNA/RNA Damage Antibody: ATTO 594 |
MBS800732-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1835 |
DNA/RNA Damage Antibody: ATTO 390 |
MBS802627-01mg |
MyBiosource |
0.1mg |
EUR 465 |
DNA/RNA Damage Antibody: ATTO 390 |
MBS802627-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1840 |
DNA/RNA Damage Antibody: ATTO 488 |
MBS804277-01mg |
MyBiosource |
0.1mg |
EUR 465 |
DNA/RNA Damage Antibody: ATTO 488 |
MBS804277-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1835 |
DNA/RNA Damage Antibody: ATTO 390 |
SMC-155D-A390 |
Stressmarq |
0.1mg |
EUR 252 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA/RNA Damage Antibody: ATTO 488 |
SMC-155D-A488 |
Stressmarq |
0.1mg |
EUR 251.3 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA/RNA Damage Antibody: ATTO 594 |
SMC-155D-A594 |
Stressmarq |
0.1mg |
EUR 251.3 |
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b |
DNA/RNA Damage Antibody, Clone 15A3 |
SMC-155C |
Stressmarq |
0.025mg |
EUR 144 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
DNA/RNA Damage Antibody: Alkaline Phosphatase |
MBS800170-01mg |
MyBiosource |
0.1mg |
EUR 460 |
DNA/RNA Damage Antibody: Alkaline Phosphatase |
MBS800170-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1800 |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-A565 |
Stressmarq |
0.1mg |
EUR 453.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-A633 |
Stressmarq |
0.1mg |
EUR 453.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-A655 |
Stressmarq |
0.1mg |
EUR 453.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-A680 |
Stressmarq |
0.1mg |
EUR 453.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-A700 |
Stressmarq |
0.1mg |
EUR 453.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-APCCY7 |
Stressmarq |
0.1mg |
EUR 540 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-DY350 |
Stressmarq |
0.1mg |
EUR 471.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-DY405 |
Stressmarq |
0.1mg |
EUR 457.2 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-DY488 |
Stressmarq |
0.1mg |
EUR 445.2 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-DY594 |
Stressmarq |
0.1mg |
EUR 447.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-DY633 |
Stressmarq |
0.1mg |
EUR 441.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-P594 |
Stressmarq |
0.1mg |
EUR 462 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594. |
Monoclonal antibody for DNA/RNA Damage |
SMC-155D-STR |
Stressmarq |
0.1mg |
EUR 451.2 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin. |
8-OHdG (DNA/RNA Damage) polyclonal antibody |
BS66180 |
Bioworld Biotech |
50ul |
EUR 358 |
|
Description: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
DNA/RNA Damage Antibody, Clone 15A3: Alkaline Phosphatase |
SMC-155D-ALP |
Stressmarq |
0.1mg |
EUR 352 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase. |
DNA/RNA Oxidative Damage |
MBS605402-0025mg |
MyBiosource |
0.025mg |
EUR 455 |
DNA/RNA Oxidative Damage |
MBS605402-01mg |
MyBiosource |
0.1mg |
EUR 675 |
DNA/RNA Oxidative Damage |
MBS605402-5x01mg |
MyBiosource |
5x0.1mg |
EUR 2880 |
Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody |
12503 |
Genovis AB |
100ug |
EUR 230 |
Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody |
12503-100 |
Genovis AB |
100ug |
EUR 230 |
Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody |
12503-500 |
Genovis AB |
500ug |
EUR 460 |
DNA and RNA Oxidative Damage Markers Monoclonal Antibody |
MBS190121-01mg |
MyBiosource |
0.1mg |
EUR 425 |
DNA and RNA Oxidative Damage Markers Monoclonal Antibody |
MBS190121-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1900 |
Anti-8-hydroxyguanosine DNA/RNA Oxidative Damage Mouse Monoclonal Antibody |
12501 |
Genovis AB |
100ug |
EUR 380 |
8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3) |
AS10-708-100 |
Agrisera AB |
100 µg |
EUR 439 |
8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3) |
AS10-708-25 |
Agrisera AB |
25 µg |
EUR 223 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx002127-100l |
Abbexa |
100 µl |
EUR 400 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx002127-20l |
Abbexa |
20 µl |
EUR 175 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx002127-50l |
Abbexa |
50 µl |
EUR 275 |
DNA Damage-Binding Protein 2 (DDB2) Antibody |
abx001528-100l |
Abbexa |
100 µl |
EUR 400 |
DNA Damage-Binding Protein 2 (DDB2) Antibody |
abx001528-20l |
Abbexa |
20 µl |
EUR 175 |
DNA Damage-Binding Protein 2 (DDB2) Antibody |
abx001528-50l |
Abbexa |
50 µl |
EUR 275 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx159468-100g |
Abbexa |
100 µg |
Ask for price |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx159468-10g |
Abbexa |
10 µg |
EUR 437.5 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx159468-50g |
Abbexa |
50 µg |
Ask for price |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx159469-100g |
Abbexa |
100 µg |
Ask for price |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx159469-10g |
Abbexa |
10 µg |
EUR 437.5 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx159469-50g |
Abbexa |
50 µg |
Ask for price |
DNA Damage-Binding Protein 2 (DDB2) Antibody |
abx338922-100l |
Abbexa |
100 µl |
EUR 250 |
DNA Damage-Binding Protein 2 (DDB2) Antibody |
20-abx338922 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 20 ug
- 50 ug
- 100 ug
- 200 ug
- 1 mg
|
|
DNA Damage-Binding Protein 2 (DDB2) Antibody |
abx338922-50l |
Abbexa |
50 µl |
EUR 162.5 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx333999-100g |
Abbexa |
100 µg |
EUR 362.5 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
20-abx333999 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 20 ug
- 50 ug
- 100 ug
- 200 ug
- 1 mg
|
|
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx333999-20g |
Abbexa |
20 µg |
EUR 162.5 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx333999-50g |
Abbexa |
50 µg |
EUR 250 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx242438-96tests |
Abbexa |
96 tests |
EUR 250 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx242444-96tests |
Abbexa |
96 tests |
EUR 250 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx232284-100g |
Abbexa |
100 µg |
EUR 350 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
abx232284-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
DNA damage-binding protein 2 (DDB2) Antibody |
abx402261-100tests |
Abbexa |
100 tests |
EUR 287.5 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx010557-100g |
Abbexa |
100 µg |
Ask for price |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx010557-10g |
Abbexa |
10 µg |
EUR 350 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx010557-200g |
Abbexa |
200 µg |
Ask for price |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx010559-100g |
Abbexa |
100 µg |
EUR 387.5 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx010559-10g |
Abbexa |
10 µg |
EUR 300 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx010559-200g |
Abbexa |
200 µg |
Ask for price |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx004988-100l |
Abbexa |
100 µl |
EUR 400 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx004988 |
Abbexa |
-
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|
- 20 ul
- 50 ul
- 100 ul
- 200 ul
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx004988-20l |
Abbexa |
20 µl |
EUR 175 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx004988-50l |
Abbexa |
50 µl |
EUR 275 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx026524-400l |
Abbexa |
400 µl |
EUR 518.75 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx026524-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx026524-80l |
Abbexa |
80 µl |
EUR 281.25 |
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx027183-400l |
Abbexa |
400 µl |
EUR 518.75 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx027183-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx027183-80l |
Abbexa |
80 µl |
EUR 250 |
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx000607-100l |
Abbexa |
100 µl |
EUR 400 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx000607 |
Abbexa |
-
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|
- 20 ul
- 50 ul
- 100 ul
- 200 ul
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx000607-20l |
Abbexa |
20 µl |
EUR 175 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx000607-50l |
Abbexa |
50 µl |
EUR 275 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx112119-100l |
Abbexa |
100 µl |
EUR 612.5 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx112119 |
Abbexa |
-
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-
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|
|
|
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
abx112120-100l |
Abbexa |
100 µl |
EUR 612.5 |
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
20-abx112120 |
Abbexa |
-
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-
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|
|
|
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
abx123209-100l |
Abbexa |
100 µl |
EUR 200 |
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
20-abx123209 |
Abbexa |
-
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-
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-
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|
- 20 ul
- 50 ul
- 100 ul
- 200 ul
|
|
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
abx123209-1ml |
Abbexa |
1 ml |
EUR 475 |
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
abx123209-200l |
Abbexa |
200 µl |
EUR 325 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx129884-100l |
Abbexa |
100 µl |
EUR 275 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx129884 |
Abbexa |
-
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|
- 10 ug
- 50 ug
- 100 ug
- 200 ug
- 1 mg
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx129884-1ml |
Abbexa |
1 ml |
EUR 775 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx129884-200l |
Abbexa |
200 µl |
EUR 350 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx103576-100g |
Abbexa |
100 µg |
EUR 750 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx103576 |
Abbexa |
-
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-
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|
- 10 ug
- 50 ug
- 100 ug
- 200 ug
- 1 mg
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx103576-20g |
Abbexa |
20 µg |
EUR 275 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx103576-50g |
Abbexa |
50 µg |
EUR 337.5 |
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
abx032764-400l |
Abbexa |
400 µl |
EUR 518.75 |
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
abx032764-80l |
Abbexa |
80 µl |
EUR 281.25 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx176186 |
Abbexa |
-
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-
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|
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx125748-100l |
Abbexa |
100 µl |
EUR 175 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx125748 |
Abbexa |
-
Ask for price
-
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-
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-
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|
- 20 ul
- 50 ul
- 100 ul
- 200 ul
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx125748-1ml |
Abbexa |
1 ml |
EUR 400 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx125748-200l |
Abbexa |
200 µl |
EUR 275 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx125750-100l |
Abbexa |
100 µl |
EUR 175 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx125750 |
Abbexa |
-
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-
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-
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-
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|
- 20 ul
- 50 ul
- 100 ul
- 200 ul
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx125750-1ml |
Abbexa |
1 ml |
EUR 400 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx125750-200l |
Abbexa |
200 µl |
EUR 275 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx329652-100g |
Abbexa |
100 µg |
Ask for price |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
20-abx329652 |
Abbexa |
-
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-
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|
|
|
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx329652-20g |
Abbexa |
20 µg |
EUR 187.5 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx329652-50g |
Abbexa |
50 µg |
EUR 250 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
abx332226-100ul |
Abbexa |
100 ul |
EUR 510 |
|
DNA/RNA Fluorescence Imaging by Artificial Nucleic Acids
Fluorescence imaging of nucleic acids is a key expertise wanted to know gene expression and the ensuing adjustments in mobile operate. This chapter focuses on sequence-specific fluorescence imaging of nucleic acids in cells utilizing fluorescent nucleic acids. The design and preparation of fluorescent nucleic acids and their utility to fluorescence imaging of intracellular nucleic acids are launched.
Staphylococcus aureus membrane vesicles comprise immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy
Gram-positive micro organism ubiquitously produce membrane vesicles (MVs), and though they contribute to organic capabilities, our data concerning their composition and immunogenicity stays restricted. Right here we study the morphology, contents and immunostimulatory capabilities of MVs produced by three Staphylococcus aureus strains; a methicillin resistant scientific isolate, a methicillin delicate scientific isolate and a laboratory-adapted pressure. We noticed variations in the quantity and morphology of MVs produced by every pressure and confirmed that they comprise microbe-associated molecular patterns (MAMPs) together with protein, nucleic acids and peptidoglycan. Evaluation of MV-derived RNA indicated the presence of small RNA (sRNA). Moreover, we detected variability within the quantity and composition of protein, nucleic acid and peptidoglycan cargo carried by MVs from every S. aureus pressure. S. aureus MVs activated Toll-like receptor (TLR) 2, 7, 8, 9 and nucleotide-binding oligomerization area containing protein 2 (NOD2) signalling and promoted cytokine and chemokine launch by epithelial cells, thus figuring out that MV-associated MAMPs together with DNA, RNA and peptidoglycan are detected by sample recognition receptors (PRRs).
Furthermore, S. aureus MVs induced the formation of and colocalized with autophagosomes in epithelial cells, whereas inhibition of lysosomal acidification utilizing bafilomycin A1 resulted in accumulation of autophagosomal puncta that colocalized with MVs, revealing the power of the host to degrade MVs by way of autophagy. This research reveals the power of DNA, RNA and peptidoglycan related to MVs to activate PRRs in host epithelial cells, and their intracellular degradation by way of autophagy. These findings advance our understanding of the immunostimulatory roles of Gram-positive bacterial MVs in mediating pathogenesis, and their intracellular destiny inside the host.
Yeasts as a promising supply platform for DNA and RNA vaccines
Yeasts are thought of a helpful system for the event of vaccines for human and veterinary well being. Species reminiscent of Saccharomyces cerevisiae and Pichia pastoris have been used efficiently as host organisms for the manufacturing of subunit vaccines. These organisms have been additionally explored as vaccine autos enabling the supply of antigens reminiscent of proteins and nucleic acids. The employed species possess a GRAS standing (Typically Acknowledged as Protected) for the manufacturing of therapeutic proteins, in addition to selling immunostimulation as a result of properties of their wall cell composition.
This technique permits the administration of nucleic acids orally and a selected supply to skilled antigen-presenting cells (APCs). On this assessment, we search to stipulate the event of entire yeast vaccines (WYV) carrying nucleic acids in several approaches within the medical area, in addition to the immunological features of this vaccine technique. The info offered right here reveal the appliance of this platform in selling efficient immune responses within the context of prophylactic and therapeutic approaches.
Nonadiabatic Absorption Spectra and Ultrafast Dynamics of DNA and RNA Photoexcited Nucleobases
We have now not too long ago proposed a protocol for Quantum Dynamics (QD) calculations, which relies on a parameterisation of Linear Vibronic Coupling (LVC) Hamiltonians with Time Dependent (TD) Density Purposeful Principle (TD-DFT), and exploits the most recent developments in multiconfigurational TD-Hartree strategies for an efficient wave packet propagation. On this contribution we discover the potentialities of this method to compute nonadiabatic vibronic spectra and ultrafast dynamics, by making use of it to the 5 nucleobases current in DNA and RNA. For all of them we computed the absorption spectra and the dynamics of ultrafast inner conversion (100 fs timescale), totally coupling the primary 2-Three shiny states and all of the shut by darkish states, for a complete of 6-9 states, and together with all the traditional coordinates.
We adopted two completely different functionals, CAM-B3LYP and PBE0, and examined the impact of the idea set. Computed spectra are in good settlement with the obtainable experimental information, remarkably bettering over pure digital computations, but additionally with respect to vibronic spectra obtained neglecting inter-state couplings. Our QD simulations point out an efficient inhabitants switch from the bottom vitality shiny excited states to the close-lying darkish excited states for uracil, thymine and adenine. Dynamics from higher-energy states present an ultrafast depopulation towards the extra steady ones. The proposed protocol is sufficiently common and automated to vow to change into helpful for widespread functions.
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