A genome-wide screen for differentially methylated long noncoding RNA

May 21, 2021
Isotype, Mouse monoclonal, precipitation, primers

Temporal panorama of human intestine RNA and DNA virome in SARS-CoV-2 an infection and severity

Background: Coronavirus illness 2019 (COVID-19) attributable to the enveloped RNA virus SARS-CoV-2 primarily impacts the respiratory and gastrointestinal tracts. SARS-CoV-2 was remoted from fecal samples, and lively viral replication was reported in human intestinal cells. The human intestine additionally harbors an unlimited quantity of resident viruses (collectively often known as the virome) that play a job in regulating host immunity and illness pathophysiology. Understanding intestine virome perturbation that underlies SARS-CoV-2 an infection and severity is an unmet want.

 

Strategies: We enrolled 98 COVID-19 sufferers with various illness severity (Three asymptomatic, 53 gentle, 34 reasonable, 5 extreme, Three crucial) and 78 non-COVID-19 controls matched for gender and co-morbidities. All topics had fecal specimens sampled at inclusion. Blood specimens had been collected for COVID-19 sufferers at admission to check for inflammatory markers and white cell counts. Amongst COVID-19 circumstances, 37 (38%) sufferers had serial fecal samples collected 2 to three instances per week from time of hospitalization till after discharge. Utilizing shotgun metagenomics sequencing, we sequenced and profiled the fecal RNA and DNA virome. We investigated alterations and longitudinal dynamics of the intestine virome in affiliation with illness severity and blood parameters.

 

Outcomes: Sufferers with COVID-19 confirmed underrepresentation of Pepper gentle mottle virus (RNA virus) and a number of bacteriophage lineages (DNA viruses) and enrichment of environment-derived eukaryotic DNA viruses in fecal samples, in comparison with non-COVID-19 topics. Such intestine virome alterations persevered as much as 30 days after illness decision. Fecal virome in SARS-CoV-2 an infection harbored extra stress-, inflammation-, and virulence-associated gene encoding capacities together with these pertaining to bacteriophage integration, DNA restore, and metabolism and virulence related to their bacterial host. Baseline fecal abundance of 10 virus species (1 RNA virus, pepper chlorotic spot virus, and 9 DNA virus species) inversely correlated with illness COVID-19 severity. These viruses inversely correlated with blood ranges of pro-inflammatory proteins, white cells, and neutrophils. Among the many 10 COVID-19 severity-associated DNA virus species, Four confirmed inverse correlation with age; 5 confirmed persistent decrease abundance each throughout illness course and after illness decision relative to non-COVID-19 topics.

 

Conclusions: Each enteric RNA and DNA virome in COVID-19 sufferers had been totally different from non-COVID-19 topics, which persevered after illness decision of COVID-19. Intestine virome might calibrate host immunity and regulate severity to SARS-CoV-2 an infection.

Our statement that intestine viruses inversely correlated with each severity of COVID-19 and host age might partly clarify that older topics are vulnerable to extreme and worse COVID-19 outcomes. Altogether, our knowledge spotlight the significance of human intestine virome in severity and probably therapeutics of COVID-19. Video Summary.

 

Optimising glyphosate tolerance in rapeseed (Brassica napus L.) by CRISPR/Cas9-based geminiviral donor DNA replicon system with Csy4-based single-guide RNA processing

 

Rapeseed (Brassica napus L.) is a vital oil crop worldwide, and efficient weed management can defend its yields and high quality. Farmers can profit from tolerant cultivars when utilizing herbicides, reminiscent of glyphosate. Amino acid substitutions in enolpyruvylshikimate-3-phosphate synthase (EPSPS) render the plant much less delicate to glyphosate. Subsequently, we aimed to optimise the glyphosate tolerance trait in rapeseed by way of endogenous EPSPS modification. To attain efficient gene substitute in B. napus L., we employed a CRISPR/Cas9 system expressing single-guide RNAs (sgRNAs) cleaved by the CRISPR-associated RNA endoribonuclease Csy4 from Pseudomonas aeruginosa for focused induction of double-strand breaks. Each the donor template and a geminiviral replicon harbouring an sgRNA expression cassette had been launched into plant cells.

Utilizing sgRNAs focusing on adjoining donor DNA template containing synonymous mutations in sgRNA websites, we achieved exact gene replacements within the endogenous B. napus EPSPS gene, BnaC04EPSPS, leading to TIPS and LFGAAGMCRL amino acid substitutions at frequencies as much as 20%. Rapeseed seedlings harbouring EPSPSmTIPS or EPSPSmLFGAAGMCRL had been glyphosate tolerant. Moreover, modifications in BnaC04EPSPS had been exactly transmitted to the following era. Our genome enhancing technique allows extremely environment friendly gene focusing on and the induction of glyphosate tolerance in oilseed rape.

bio-tech-inc

bio-tech-inc

DNA Oxidative Damage Kit - Quantitative
DN-002 20 tests
EUR 656

OxiSelect™ Oxidative DNA Damage Quantitation Kit (AP sites)
STA-324 50 assays
EUR 580

OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation)
STA-320 96 assays
EUR 736
Description: Excepted Quantities

OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation)
STA-320-5 5 x 96 assays
EUR 3160
Description: Excepted Quantities

OxiSelect Oxidative DNA Damage Quantitation Kit (AP Sites), Trial Size
STA-324-T 10 assays
EUR 498
Description: DNA damage can manifest in the formation of apurinic or apyrimidinic (AP or abasic) sites. Such spontaneous base loss in mammalian cells has been estimated at between 50,000 and 200,000 sites per day. Unrepaired abasic sites can inhibit transcription and may be mutagenic. Our OxiSelect Oxidative DNA Damage Quantitation Kit provides a simple, user-friendly method for the quantitaiton DNA damage in the form of abasic sites. The assay uses an Aldehyde Reactive Probe (ARP) to specifically react with an aldehyde group on the open ring of the AP site. This allows the AP site to be labeled with Biotin, followed by detection with Streptavidin-Enzyme conjugate.

OxiSelect Oxidative RNA Damage ELISA Kit (8-OHG Quantitation) (96 tests)
MBS168447-5x96Assays 5x96Assays
EUR 4465

OxiSelect Oxidative RNA Damage ELISA Kit (8-OHG Quantitation) (96 tests)
MBS168447-96Assays 96Assays
EUR 1125

OxiSelect Oxidative RNA Damage ELISA Kit (8-OHG Quantitation), Trial Size
STA-325-T 32 assays
EUR 609.6
Description: Recently oxidative RNA damage has been described in conjunction with a wide variety of neurological diseases including Alzheimer?s disease, Parkinson?s disease, Dementia with Lewy Bodies, prion disease, and subacute sclerosing panencephalitis. We have developed an easy-to-use ELISA for the detection of the most common marker of RNA damage: 8-hydroxyguanosine (8-OHG).

OxiSelect Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation) (1 plate)
MBS168191-32Assays 32Assays
EUR 615

OxiSelect Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation) (1 plate)
MBS168191-5x96Assays 5x96Assays
EUR 4465

OxiSelect Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation) (1 plate)
MBS168191-96Assays 96Assays
EUR 1125

OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation) (96 tests)
STA-325 96 assays
EUR 736
Description: Excepted Quantities

OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation) (5x96 tests)
STA-325-5 5 x 96 assays
EUR 3160
Description: Excepted Quantities

OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation), Trial Size
STA-320-T 32 assays
EUR 368
Description: Excepted Quantities

DNA/RNA Damage Antibody, 15A3; Anti-DNA/RNA Damage Antibody
MBS802475-0025mg 0.025mg
EUR 265

DNA / RNA Damage Antibody
abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444884-100l 100 µl
EUR 337.5

DNA / RNA Damage Antibody
20-abx444884
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  • 25 ug
  • 100 ug

DNA / RNA Damage Antibody
abx440040-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440321-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440602-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440883-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441164-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441445-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody
abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody
abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442850-100ug 100 ug
EUR 661.2

DNA/RNA Damage Antibody
MBS8001907-0025mg 0.025mg
EUR 265

DNA/RNA Damage Antibody
MBS8001907-5x0025mg 5x0.025mg
EUR 925

DNA/RNA Damage Antibody
MBS801590-01mg 0.1mg
EUR 415

DNA/RNA Damage Antibody
MBS801590-5x01mg 5x0.1mg
EUR 1595

DNA/RNA Damage Antibody
SMC-155D 0.1mg
EUR 214.2
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody
SMC-155S 0.012mg Ask for price
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
abx005629-100l 100 µl
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
20-abx005629
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
20-abx320325
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  • 50 ul
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
20-abx321453
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  • 50 ul
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
abx321453-50g 50 µg
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DNA / RNA Damage Antibody (PE)
abx444253-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (HRP)
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EUR 562.5

DNA / RNA Damage Antibody (APC)
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DNA/RNA Damage Antibody: HRP
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DNA/RNA Damage Antibody: APC
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EUR 250.6
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody: HRP
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EUR 241.5
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

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EUR 248.5
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (FITC)
abx443130-100g 100 µg
EUR 575

DNA/RNA Damage Antibody: FITC
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DNA/RNA Damage Antibody: FITC
SMC-155D-FITC 0.1mg
EUR 245
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (PerCP)
abx443972-100g 100 µg
EUR 575

DNA/RNA Damage Antibody: PerCP
MBS802697-01mg 0.1mg
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DNA/RNA Damage Antibody: PerCP
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EUR 1830

DNA/RNA Damage Antibody: PerCP
SMC-155D-PCP 0.1mg
EUR 250.6
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (Biotin)
abx442850-100g 100 µg
EUR 575

DNA/RNA Damage Antibody: Biotin
MBS803145-01mg 0.1mg
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DNA/RNA Damage Antibody: Biotin
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EUR 1815

DNA/RNA Damage Antibody: Biotin
SMC-155D-BI 0.1mg
EUR 247.8
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (ATTO390)
abx440040-200g 200 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO488)
abx440321-100g 100 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO594)
abx440883-100g 100 µg
EUR 587.5

DNA/RNA Damage Antibody: ATTO 594
MBS800732-01mg 0.1mg
EUR 465

DNA/RNA Damage Antibody: ATTO 594
MBS800732-5x01mg 5x0.1mg
EUR 1835

DNA/RNA Damage Antibody: ATTO 390
MBS802627-01mg 0.1mg
EUR 465

DNA/RNA Damage Antibody: ATTO 390
MBS802627-5x01mg 5x0.1mg
EUR 1840

DNA/RNA Damage Antibody: ATTO 488
MBS804277-01mg 0.1mg
EUR 465

DNA/RNA Damage Antibody: ATTO 488
MBS804277-5x01mg 5x0.1mg
EUR 1835

DNA/RNA Damage Antibody: ATTO 390
SMC-155D-A390 0.1mg
EUR 252
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody: ATTO 488
SMC-155D-A488 0.1mg
EUR 251.3
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody: ATTO 594
SMC-155D-A594 0.1mg
EUR 251.3
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody, Clone 15A3
SMC-155C 0.025mg
EUR 144
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

OASE00080-25UG - DNA/RNA Damage Antibody
OASE00080-25UG 25ug
EUR 199

OASE00081-100UG - DNA/RNA Damage Antibody
OASE00081-100UG 100ug
EUR 399

DNA/RNA Damage Antibody: Alkaline Phosphatase
MBS800170-01mg 0.1mg
EUR 460

DNA/RNA Damage Antibody: Alkaline Phosphatase
MBS800170-5x01mg 5x0.1mg
EUR 1800

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

8-OHdG (DNA/RNA Damage) polyclonal antibody
BS66180 50ul
EUR 358
Description: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

DNA/RNA Damage Antibody, Clone 15A3: Alkaline Phosphatase
SMC-155D-ALP 0.1mg
EUR 352
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx114290-100l 100 µl
EUR 612.5

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx146245-1096tests 10 × 96 tests Ask for price

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx146245-596tests 5 × 96 tests Ask for price

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx146245-96tests 96 tests
EUR 337.5

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx325277-100g 100 µg
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx325277-50g 50 µg
EUR 187.5

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx325602-100g 100 µg
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx325602-50g 50 µg
EUR 187.5

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx213481-10l 10 µl
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx212012-100l 100 µl
EUR 350

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx212012-50l 50 µl
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody
abx236055-100g 100 µg
EUR 350

Human DNA Oxidative Demethylase ALKBH2 (ALKBH2) Protein
abx073206-20kDa1g 20 kDa; 1 g
EUR 225

Human DNA Oxidative Demethylase ALKBH2 (ALKBH2) Protein
abx073206-20kDa5g 20 kDa; 5 g
EUR 3550

Human DNA Oxidative Demethylase ALKBH2 (ALKBH2) Protein
abx073206-40kDa1g 40 kDa; 1 g
EUR 325

Oxidative-Stress Responsive 1 (OXSR1) Antibody
20-abx114290
  • Ask for price
  • Ask for price
  • 50 ul
  • 150 ul

Recombinant Human DNA oxidative demethylase ALKBH2 (ALKBH2)
CSB-EP761219HU 4107 mg Ask for price

 

A genome-wide display screen for differentially methylated lengthy noncoding RNAs recognized that lncAC007255.Eight is regulated by promoter DNA methylation in Beas-2B cells malignantly reworked by NNK

 

Tobacco publicity is well-known to induce genetic and epigenetic adjustments that contribute to the pathogenesis of lung most cancers. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a major tobacco-specific carcinogen, however the oncogenic mechanisms of NNK haven’t been totally elucidated. On this research we discovered that DNA methyltransferase 1(DNMT1) was overexpressed in malignantly reworked human bronchial epithelial Beas-2B cells induced by NNK (2B-NNK cells), by remedy with NNK (400 μg/ml) for 7 days. An Arraystar Human noncoding RNA Promoter Microarray was used to detect the DNA methylation standing of the promoter area of lengthy noncoding RNAs (lncRNAs). The consequence confirmed that 1010 differentially methylated fragments had been current within the lncRNA promoter area. QRT-PCR revealed that the expression of lncRNA AC007255.Eight was remarkably downregulated in 2B-NNK cells and lung most cancers tissues.

Moreover, Methylation-particular PCR confirmed that the methylation of the lncRNA AC007255.Eight promoter was elevated in 2B-NNK cells and lung most cancers tissues. The decreased expression of lncRNA AC007255.Eight was considerably related to hypermethylation of lncRNA AC007255.Eight promoter area. LncRNA AC007255.Eight overexpression might lead to decreased cell proliferation and elevated cell apoptosis in 2B-NNK cells.

In conclusion, NNK induced lncRNA AC007255.8 promoter hypermethylation by way of upregulation of DNMT1 in Beas-2B cells, resulting in downregulation of lncRNA AC007255.8, and finally the enhancement of cell proliferation and the inhibition of apoptosis. This analysis affords novel insights into the epigenetic mechanisms of lung most cancers, and can stimulate additional analysis into the involvement of aberrant DNA methylation of non-coding areas of the genome within the pathogenesis of lung most cancers

 

Systematic comparability and prediction of the consequences of missense mutations on protein-DNA and protein-RNA interactions

 

The binding affinities of protein-nucleic acid interactions could possibly be altered as a result of missense mutations occurring in DNA- or RNA-binding proteins, due to this fact leading to varied ailments. Sadly, a scientific comparability and prediction of the consequences of mutations on protein-DNA and protein-RNA interactions (these two mutation lessons are termed MPDs and MPRs, respectively) remains to be missing. Right here, we demonstrated that these two lessons of mutations might generate related or totally different tendencies for binding free power adjustments by way of the properties of mutated residues. We then developed regression algorithms individually for MPDs and MPRs by introducing novel geometric partition-based power options and interface-based structural options.

By function choice and ensemble studying, related computational frameworks that built-in energy- and nonenergy-based fashions had been established to estimate the binding affinity adjustments ensuing from MPDs and MPRs, however the chosen options for the closing fashions had been totally different and due to this fact mirrored the specificity of those two mutation lessons.

Moreover, the proposed methodology was prolonged to the identification of mutations that considerably decreased the binding affinities. In depth validations indicated that our algorithm typically carried out higher than the state-of-the-art strategies on each the regression and classification duties. The webserver and software program are freely obtainable at http://liulab.hzau.edu.cn/PEMPNI and https://github.com/hzau-liulab/PEMPNI.

 

Detecting protein and DNA/RNA constructions in cryo-EM maps of intermediate decision utilizing deep studying

 

An growing variety of density maps of macromolecular constructions, together with proteins and DNA/RNA complexes, have been decided by cryo-electron microscopy (cryo-EM). Though these days maps at a near-atomic decision are routinely reported, there are nonetheless substantial fractions of maps decided at intermediate or low resolutions, the place extracting construction data shouldn’t be trivial. Right here, we report a brand new computational technique, Emap2sec+, which identifies DNA or RNA as nicely because the secondary constructions of proteins in cryo-EM maps of 5 to 10 Å decision.

Emap2sec+ employs the deep Residual convolutional neural community. Emap2sec+ assigns structural labels with related chances at every voxel in a cryo-EM map, which is able to assist construction modeling in an EM map. Emap2sec+ confirmed steady and excessive project accuracy for nucleotides in low decision maps and improved efficiency for protein secondary construction assignments than its earlier model when examined on simulated and experimental maps.

 

 

DNA / RNA Damage Antibody (ATTO488)
abx440321-100g 100 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO594)
abx440883-100g 100 µg
EUR 587.5

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 655)
abx441478-100ug 100 ug
EUR 661.2

DNA/RNA Damage Antibody, 15A3; Anti-DNA/RNA Damage Antibody
MBS802475-0025mg 0.025mg
EUR 265

DNA / RNA Damage Antibody
abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444884-100l 100 µl
EUR 337.5

DNA / RNA Damage Antibody
20-abx444884
  • Ask for price
  • Ask for price
  • 25 ug
  • 100 ug

DNA / RNA Damage Antibody
abx440040-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440321-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440602-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440883-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441164-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441445-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody
abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody
abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442850-100ug 100 ug
EUR 661.2

DNA/RNA Damage Antibody
MBS8001907-0025mg 0.025mg
EUR 265

DNA/RNA Damage Antibody
MBS8001907-5x0025mg 5x0.025mg
EUR 925

DNA/RNA Damage Antibody
MBS801590-01mg 0.1mg
EUR 415

DNA/RNA Damage Antibody
MBS801590-5x01mg 5x0.1mg
EUR 1595

DNA/RNA Damage Antibody
SMC-155D 0.1mg
EUR 214.2
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody
SMC-155S 0.012mg Ask for price
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (PE)
abx444253-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (HRP)
abx443410-100g 100 µg
EUR 562.5

DNA / RNA Damage Antibody (APC)
abx442569-100l 100 µl
EUR 575

DNA/RNA Damage Antibody: HRP
MBS801864-01mg 0.1mg
EUR 450

DNA/RNA Damage Antibody: HRP
MBS801864-5x01mg 5x0.1mg
EUR 1770

DNA/RNA Damage Antibody: RPE
MBS803622-01mg 0.1mg
EUR 460

DNA/RNA Damage Antibody: RPE
MBS803622-5x01mg 5x0.1mg
EUR 1820

DNA/RNA Damage Antibody: APC
SMC-155D-APC 0.1mg
EUR 250.6
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody: HRP
SMC-155D-HRP 0.1mg
EUR 241.5
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA/RNA Damage Antibody: RPE
SMC-155D-RPE 0.1mg
EUR 248.5
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (FITC)
abx443130-100g 100 µg
EUR 575

DNA/RNA Damage Antibody: FITC
MBS803261-01mg 0.1mg
EUR 455

DNA/RNA Damage Antibody: FITC
MBS803261-5x01mg 5x0.1mg
EUR 1790

DNA/RNA Damage Antibody: FITC
SMC-155D-FITC 0.1mg
EUR 245
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (PerCP)
abx443972-100g 100 µg
EUR 575

DNA/RNA Damage Antibody: PerCP
MBS802697-01mg 0.1mg
EUR 465

DNA/RNA Damage Antibody: PerCP
MBS802697-5x01mg 5x0.1mg
EUR 1830

DNA/RNA Damage Antibody: PerCP
SMC-155D-PCP 0.1mg
EUR 250.6
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

DNA / RNA Damage Antibody (Biotin)
abx442850-100g 100 µg
EUR 575

DNA/RNA Damage Antibody: Biotin
MBS803145-01mg 0.1mg
EUR 460

DNA/RNA Damage Antibody: Biotin
MBS803145-5x01mg 5x0.1mg
EUR 1815

DNA/RNA Damage Antibody: Biotin
SMC-155D-BI 0.1mg
EUR 247.8
Description: Mouse Anti- DNA/RNA Damage Monoclonal IgG2b

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 390)
abx440073-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 488)
abx440354-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 565)
abx440635-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 594)
abx440916-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 633)
abx441197-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 680)
abx441759-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 700)
abx442040-100ug 100 ug
EUR 661.2

DNA/RNA Damage Antibody, Clone 15A3
SMC-155C 0.025mg
EUR 144
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (PE/ATTO 594)
abx443724-100ug 100 ug
EUR 678

OASE00080-25UG - DNA/RNA Damage Antibody
OASE00080-25UG 25ug
EUR 199

OASE00081-100UG - DNA/RNA Damage Antibody
OASE00081-100UG 100ug
EUR 399

DNA/RNA Damage Antibody: Alkaline Phosphatase
MBS800170-01mg 0.1mg
EUR 460

DNA/RNA Damage Antibody: Alkaline Phosphatase
MBS800170-5x01mg 5x0.1mg
EUR 1800

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

WSC-2900 Rotator ATTO
4002900 each
EUR 569.5
Description: Test Tube Rotator

8-OHdG (DNA/RNA Damage) polyclonal antibody
BS66180 50ul
EUR 358
Description: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

ATTO Polyolefine Tube 5m (1pc)
1221464 each
EUR 125.96
Description: 2 mm I.D. - 4 mm O.D.

ATTO Polyolefine Tube 5m (1pc)
1221470-1 each
EUR 132.66
Description: 4 mm I.D. - 6 mm O.D.

DNA/RNA Damage Antibody, Clone 15A3: Alkaline Phosphatase
SMC-155D-ALP 0.1mg
EUR 352
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

ATTO Polyolefine Tube with Lure fitting (10pcs)
1221462 each
EUR 105.86
Description: 4 mm I.D. - 6 mm O.D.

ATTO Polyolefine Tube with Lure fitting (10pcs)
1221463 each
EUR 99.16
Description: 2 mm I.D. - 4 mm O.D.

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO390)
abx440073-200g 200 µg
EUR 587.5

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO488)
abx440354-100g 100 µg
EUR 587.5

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO594)
abx440916-100g 100 µg
EUR 587.5

DNA/RNA Oxidative Damage
MBS605402-0025mg 0.025mg
EUR 455

DNA/RNA Oxidative Damage
MBS605402-01mg 0.1mg
EUR 675

DNA/RNA Oxidative Damage
MBS605402-5x01mg 5x0.1mg
EUR 2880

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody
12503 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody
12503-100 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody
12503-500 500ug
EUR 460

DNA and RNA Oxidative Damage Markers Monoclonal Antibody
MBS190121-01mg 0.1mg
EUR 425

DNA and RNA Oxidative Damage Markers Monoclonal Antibody
MBS190121-5x01mg 5x0.1mg
EUR 1900

Anti-8-hydroxyguanosine DNA/RNA Oxidative Damage Mouse Monoclonal Antibody
12501 100ug
EUR 380

DNA Methyltransferase 1 (DNMT1) Antibody (ATTO 655)
abx444797-100ug 100 ug
EUR 693.6

DNA Methyltransferase 1 (DNMT1) Antibody (ATTO 655)
abx441480-100ug 100 ug
EUR 693.6

DNA Methyltransferase 1 (DNMT1) Antibody (ATTO 655)
abx441490-100ug 100 ug
EUR 678

AB-1171 ATTOPREP MF
3521370 1unit
EUR 206.36
Description: Centrifuge Tube filter device

WSE-7040 EzApply DNA
2332394 4unit
EUR 36.85
Description: 1bottle

8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3)
AS10-708-100 100 µg
EUR 439

8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3)
AS10-708-25 25 µg
EUR 223

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx002127-100l 100 µl
EUR 400

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx002127-20l 20 µl
EUR 175

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx002127-50l 50 µl
EUR 275

DNA Damage-Binding Protein 2 (DDB2) Antibody
abx001528-100l 100 µl
EUR 400

DNA Damage-Binding Protein 2 (DDB2) Antibody
abx001528-20l 20 µl
EUR 175

DNA Damage-Binding Protein 2 (DDB2) Antibody
abx001528-50l 50 µl
EUR 275

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx159468-100g 100 µg Ask for price

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx159468-10g 10 µg
EUR 437.5

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx159468-50g 50 µg Ask for price

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx159469-100g 100 µg Ask for price

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx159469-10g 10 µg
EUR 437.5

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx159469-50g 50 µg Ask for price

DNA Damage-Binding Protein 2 (DDB2) Antibody
abx338922-100l 100 µl
EUR 250

DNA Damage-Binding Protein 2 (DDB2) Antibody
20-abx338922
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 20 ug
  • 50 ug
  • 100 ug
  • 200 ug
  • 1 mg

DNA Damage-Binding Protein 2 (DDB2) Antibody
abx338922-50l 50 µl
EUR 162.5

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx333999-100g 100 µg
EUR 362.5

DNA Damage-Binding Protein 1 (DDB1) Antibody
20-abx333999
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 20 ug
  • 50 ug
  • 100 ug
  • 200 ug
  • 1 mg

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx333999-20g 20 µg
EUR 162.5

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx333999-50g 50 µg
EUR 250

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx242438-96tests 96 tests
EUR 250

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx242444-96tests 96 tests
EUR 250

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx232284-100g 100 µg
EUR 350

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx232284-100ug 100 ug
EUR 577.2

DNA damage-binding protein 2 (DDB2) Antibody
abx402261-100tests 100 tests
EUR 287.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx010557-100g 100 µg Ask for price

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx010557-10g 10 µg
EUR 350

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx010557-200g 200 µg Ask for price

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx010559-100g 100 µg
EUR 387.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx010559-10g 10 µg
EUR 300

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx010559-200g 200 µg Ask for price

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx004988-100l 100 µl
EUR 400

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx004988
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 20 ul
  • 50 ul
  • 100 ul
  • 200 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx004988-20l 20 µl
EUR 175

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx004988-50l 50 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-400l 400 µl
EUR 518.75

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-80l 80 µl
EUR 281.25

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-400l 400 µl
EUR 518.75

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-80l 80 µl
EUR 250

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx000607-100l 100 µl
EUR 400

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx000607
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 20 ul
  • 50 ul
  • 100 ul
  • 200 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx000607-20l 20 µl
EUR 175

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx000607-50l 50 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx112119-100l 100 µl
EUR 612.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx112119
  • Ask for price
  • Ask for price
  • 50 ul
  • 150 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
abx112120-100l 100 µl
EUR 612.5

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx112120
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  • 50 ul
  • 150 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
abx123209-100l 100 µl
EUR 200

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx123209
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  • 20 ul
  • 50 ul
  • 100 ul
  • 200 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
abx123209-1ml 1 ml
EUR 475

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
abx123209-200l 200 µl
EUR 325

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx129884-100l 100 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx129884
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  • 10 ug
  • 50 ug
  • 100 ug
  • 200 ug
  • 1 mg

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx129884-1ml 1 ml
EUR 775

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx129884-200l 200 µl
EUR 350

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx103576-100g 100 µg
EUR 750

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx103576
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  • 10 ug
  • 50 ug
  • 100 ug
  • 200 ug
  • 1 mg

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx103576-20g 20 µg
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx103576-50g 50 µg
EUR 337.5

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
abx032764-400l 400 µl
EUR 518.75

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
abx032764-80l 80 µl
EUR 281.25

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx176186
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  • 200 ug
  • 1 mg

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx125748-100l 100 µl
EUR 175

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125748
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  • 20 ul
  • 50 ul
  • 100 ul
  • 200 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx125748-1ml 1 ml
EUR 400

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx125748-200l 200 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx125750-100l 100 µl
EUR 175

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125750
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  • 20 ul
  • 50 ul
  • 100 ul
  • 200 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx125750-1ml 1 ml
EUR 400

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx125750-200l 200 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx329652-100g 100 µg Ask for price

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx329652
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  • 50 ug
  • 100 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx329652-20g 20 µg
EUR 187.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx329652-50g 50 µg
EUR 250

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx332226-100ul 100 ul
EUR 510

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx172142
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  • 200 ug
  • 1 mg

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx172142-1ml 1 ml
EUR 787.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx301173-100g 100 µg
EUR 362.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx301173
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  • 20 ug
  • 50 ug
  • 100 ug
  • 200 ug
  • 1 mg

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx301173-20g 20 µg
EUR 162.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx301173-50g 50 µg
EUR 250

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx326210-100g 100 µg
EUR 250

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx326210
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  • 50 ug
  • 100 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx326210-50g 50 µg
EUR 187.5

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
abx241498-100g 100 µg
EUR 350

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx241498
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  • 50 ul
  • 100 ul
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